Novu Framework works out of the box with Nuxt.js. You can use the @novu/framework/nuxt package to serve your Bridge endpoint in your Nuxt.js application. For a boilerplate project with Vue Email, view: Nuxt.js Boilerplate 
import { serve } from "@novu/framework/nuxt";
import { myWorkflow } from "../workflows";

export default defineEventHandler(serve({ workflows: [myWorkflow] }));
Check out a comprehensive guide on sending notifications in Nuxt with Vuemail.